| HIV
TRANSMISSION FROM MOTHER TO CHILD RESULTING FROM MEDICAL
MALPRACTICE
Tragically,
every year children are born with HIV or acquire HIV shortly after
birth due to medical malpractice. In many cases, the mother does
not know during the pregnancy that she is HIV positive. Yet, the
mother's history can include factors that make the transmission of
HIV to her child likely. In some cases, the mother has symptoms of
HIV that are undiagnosed and untreated by doctors and nurses
during prenatal care and delivery. In other cases, the doctors and
nurses actually know that the mother is HIV positive, but do not
provide proper treatment to prevent transmission to the child.
What Is
HIV
HIV, also
known as The Human Immunodeficiency Virus, causes AIDS by
attacking the immune system and leaving the body vulnerable to a
variety of life-threatening illnesses and cancers. Common
bacteria, yeast, parasites, and viruses that ordinarily do not
cause serious disease in people with fully functional immune
systems can cause fatal illnesses in people with AIDS.
People who
become infected with HIV may have no symptoms for up to ten years,
but they can still transmit the infection to others. Meanwhile,
their immune system gradually weakens until they are diagnosed
with AIDS. Acute HIV infection progresses over time to
asymptomatic HIV infection, then to early symptomatic HIV
infection and later, to AIDS (very advanced HIV infection). Most
individuals infected with HIV will progress to AIDS if not
treated. However, there is a very small subset of patients who
develop AIDS very slowly or never at all. These patients are
called non-progressors.
HIV
Transmission from Mother to Child
It is
possible for an HIV-infected mother to pass the virus directly to
her child before or during birth (known as "perinatal"
transmission), or through breast milk. Approximately 20% of babies
born to HIV-positive women who are not treated with
transmission-reduction measures will be infected with HIV virus.
The breast
milk of an HIV-infected mother contains the HIV virus, and while
small amounts of breast milk do not pose significant threat of
infection to adults, it is a viable means of transmission to
infants. Approximately 5% of vertical transmission occurs via
breast milk.
Prevention
of HIV Transmission from Mother to Child
The first
step in preventing the transmission of HIV from mother to child is
to recognize that the mother is HIV infected. A pregnant woman may
exhibit symptoms of HIV infection which should then result in
treatment to prevent transmission of the virus to her child. Some
of the early symptoms of HIV infection and AIDS that a pregnant
woman may exhibit can include:
• Herpes
Simplex Virus - causing ulcers in the mouth or genitals
• Tuberculosis - infection by the tuberculosis bacteria
that predominately affects the lungs
• Oral or vaginal thrush - yeast infection of the mouth
or genitals
• Herpes zoster - ulcers over a discrete patch of skin
caused by this virus
• Non-Hodgkins Lymphoma - cancer of the lymph glands
If a woman
who is pregnant demonstrates symptoms of the HIV virus,
appropriate treatment should be provided before and during birth,
and the mother should be advised not to breast feed her child. By
administering AZT during the later stages of pregnancy and
delivery, the probability that the HIV virus will be transmitted
to the child is reduced to 5% - 8%. By performing a caesarian
section (c-section) during delivery in addition to AZT therapy,
transmission can be reduced to less than 2%. Because it is
possible for the mother to transmit the HIV virus after delivery
through breast milk, doctors and nurses should also advise the
mother not to breast feed her child. Studies are currently being
conducted to determine whether vaginal cleansing and the use of
antiviral vaginal suppositories prior to birth may also be
effective in reducing mother-to-child, or "perinatal,"
transmission.
Treatment
For Children with HIV infection
Combination
antiretroviral therapy with such drugs as zidovudine and
didanosine, zidovudine and lamivudine, or didanosine and stavudine
with protease inhibitor-containing triple combinations, can
significantly provide both immunologic and virologic benefits.
Such combination therapies confer significant survival benefits in
infected children.
Children
should be followed with blood work frequently after beginning
antiretroviral therapy. Complications of antiretroviral therapy in
children include myopathy, pancreatitis, dyslipidemia, insulin
resistance, glucose intolerance, changes in body shape, and lactic
acidosis. Routine clinical monitoring should thus include liver
enzymes, and a complete blood count for glucose, electrolytes and
anion gap, total cholesterol, and triglycerides.
Vaccinations
should include Haemophilus influenzae and pneumococcal conjugate
vaccines as encapsulated bacteria cause considerable morbidity for
HIV-infected children. Pneumococcal conjugate vaccine is
recommended for children 2 to 5 years of age who have not already
received it, followed by 23-valent pneumococcal polysaccharide
vaccine. Varicella vaccine, a live virus vaccine, can be
considered for HIV-infected children without immunosuppression.
Measles, mumps and the rubella vaccine can be safely given to
HIV-infected children who do not have severe immunosuppression.
Life
Expectancy For Children with HIV infection
The course
of HIV and the life expectancy of a child with HIV can vary
greatly. There are two major groups of children with HIV. One
group consists of rapid progressors, who develop symptoms early in
life, develop serious complications and AIDS early and often die
before the age of five. The other group consists of long term
survivors, who generally develop symptoms much later (some not
until their early teens) and live longer. Generally, children with
perinatal infection do not survive beyond their early 20's. The
median survival age is 8 to 9 years.
If Your
Child Has HIV
If your
child suffers from HIV as a result of medical malpractice, you
should contact a competent lawyer immediately. The lawyer will be
able to work with you to determine whether there were signs that
HIV could be transmitted to your child and whether your doctors
should have provided treatment. |